Ivor-Lewis手术辅助放疗对ⅡA期中段食管癌局部控制的
临床研究
张明月;王洲;刘相燕;陈钢;刘凡英
【期刊名称】《中华外科杂志》 【年(卷),期】2008(046)014
【摘要】目的 探讨Ivor-Lewis手术后辅助放疗对ⅡA期胸中段食管鳞状细胞癌的局部控制作用.方法 回顾性分析1999年6月至2002年6月间接受Ivor-Lewis手术治疗的125例ⅡA期胸中段食管鳞状细胞癌患者的临床资料.Kaplan-meier法计算生存率,X2检验比较不同辅助治疗方案的肿瘤局部复发率差别.结果 本组患者3年和5年生存率分别为58.4%和43.2%.3年内61例(48.8%)肿瘤复发,其中局部-区域性复发38例(30.4%).手术后辅助放疗组局部复发率20.3%,低于手术后辅助化疗组的40.6%和未经辅助治疗组的41.4%(P<0.05).结论 Ivor-Lewis手术辅助术后放疗,是对ⅡA期胸中段食管鳞状细胞癌实现局部控制的有效方法.%Objective To investigate the local control of radiotherapy following lvor-Lewis esophagectomy in the patients with stage Ⅱ A middle-third thoracic esophageal cancer. Methods From June 1999 to June 2002, 125 patients with stage Ⅱ A squamous cell carcinoma of the middle-third thoracic esophagus were treated
with
Ivor-Lewis
esophagectomy
with
two-fields
lymphadenectomy. The survival rate was calculated by Kaplan-meier method and the difference of recurrence rate compared by X2> test. Results The 3-year and 5-year survival rates were 58.4% and 43. 2% in
Ivor-Lewis手术辅助放疗对ⅡA期中段食管癌局部控制的临床研究
