冠状动脉内半剂量替罗非班对老年急诊介入术中慢血流的
安全性及有效性研究
高玉龙;王春梅;朱小玲;艾辉;李艳芳
【期刊名称】《中华老年心脑血管病杂志》 【年(卷),期】2013(015)004
【摘要】目的 观察冠状动脉内注射半剂量替罗非班对老年ST段抬高心肌梗死(STEMI)接受急诊PCI患者术中慢血流的有效性及安全性.方法 选择因STEMI住院行急诊PCI术,并于术中出现慢血流患者共217例,根据冠状动脉内应用替罗非班的剂量分为半剂量组(5 μg/kg)126例和常规剂量组(10 μg/kg)91例,比较2组一般临床特点,分析有效性及安全性.结果 半剂量组轻度出血比例明显低于常规剂量组(1.6％ vs 7.7％,P＜0.05).而2组患者LVEF、ST段回落、中度出血及院内病死率比较差异无统计学意义(P＞0.05).结论 针对老年STEMI患者的临床特点,急诊PCI过程中出现慢血流时选择冠状动脉内应用半剂量替罗非班安全、有效.%Objective To study the safety and effect of 50% tirofiban dose on slow flow in elderly patients with acute myocardial infarction(AMI) during emergency percutaneous coronary inter-vention(PCI). Methods Two hundred and seventeen AMI patients with slow flow during emergency PCI for ST-segment elevation were divided into 50% tirofiban dose (5 μg/kg) group (n = 126) and routine tirofiban dose(10 μg/kg) group. Their clinical features and the safety and effect of tirofiban were compared and analyzed. Results The incidence of mild bleeding was significantly lower in 50%tirofiban dose group than in
冠状动脉内半剂量替罗非班对老年急诊介入术中慢血流的安全性及有
