Journal
山东医学高等专科学校学报2019,41(3):165-167of Shandong Medical College利多卡因凝胶在膀胱灌注化疗中的应用研究杜金霞（临沂市中医医院，山东 临沂276000）摘要：目的 探讨TURBT术后并发症的控制方法。方法 收集行TURBT术且术后行膀胱药
物灌注化疗的老年男性患者60例，将其随机分为观察组和对照组，各30例。观察组应用利多卡因 凝胶作为注药尿管表面润滑剂，对照组以石蜡油为表面润滑剂，观察两组患者的一次性置管成功率 及术后不良反应的发生情况。结果观察组在一次性置管成功率、药物保留时间及灌注化疗周期完
成率均优于对照组（x2—4. 51?6. 29, P <0. 05）,膀胱刺激症状发生率低于对照组（X2—4. 31，P
— 0.038）。结论应用利多卡因凝胶作为注药导管的表面润滑剂能够降低不良反应的发生。关键词：膀胱灌注；膀胱肿瘤；利多卡因凝胶中图分类号:R 737. 14 文献标识码:A 文章编号= 1674-0947（2019）03-0165-03网络出版时间：2019-04-16 17：17：20doi：10. 3969/j. issn. 1674-0947. 2019. 03. 003
网络出版地址：http ://kns. cnki. net/kcms/detail/37. 1451. R . 20190416. 1716. 014. htmlAPPLICATION OF LIDOCAINE GEL IN INTRAVESICAL CHEMOTHERAPYDU Jin-xia(.Linyi Traditional Chinese Medicine Hospital ,Linyi 276000 , China)Abstract: Objective To investigate the control methods of postoperative complications of TURBT . Methods Sixty elderly male patients who underwent TURBT and received bladder drug infusion chemother-
apy were randomly divided into observation group and control group, 30 cases each. The observation group
was treated with lidocaine gel as the lubricant for the surface of the catheter, and the control group was treated with paraffin oll as the surface lubricant. The success rate of one-time catheterization and the inci-
dence of postoperative adverse reactions were observed . Results In the observation group, the success rate of one-time catheterization, drug retention time and perfusion chemotherapy cycle were higher than the control group (^2— 4. 51?6. 29, P <0. 05) , and the incidence of bladder irritation was lower than that of
the control group (^2 — 4. 31, P =0. 038). Conclusion The use of lidocaine gel as a surface lubricant for in-
jection catheters can reduce the incidence of adverse reactions.Key words:Intravesical instillation；Bladder tumor；Lidocaine gel膀胱肿瘤泌尿系统最常见，非肌层浸润性膀胱
少对尿道粘膜的刺激及患者的疼痛2 ,同时增加患 者对周期性灌注化疗的依从性。癌约占其70%，经尿道膀胱肿瘤电切术（TURBT） 是该病的重要诊治方法，但术后复发或进展率高[1],
1资料与方法11
2016
术后辅助膀胱灌注化疗可有效降低其复发。但有较
1 -2019 1多不良反应，增加了患者对膀胱灌注治疗的恐惧。 盐酸利多卡因凝胶具有表面麻醉和润滑作用，可减作者简介：杜金霞，女，本科，副主任护师，研究方向：护理
月入院的60例男性患者的临床资料。所有患者均
接受TURBT术，术后病理为非肌层浸润性尿路上 皮癌（包括TIS,Ta,T1）,年龄（61士6. 8）岁。两组
患者既往均无泌尿系统外伤及导尿病史。将其随机
外科学。收稿日期：2019-03-11
分为观察组和对照组，各30例。1.2方法 灌注方案：根据患者术后病理类型，依
利多卡因凝胶在膀胱灌注化疗中的应用研究
