Antibacterial activities of selected medicinal plants in traditional treatment of human wo

Antibacterial activities of selected medicinal plants

in traditional treatment of human wounds in

Ethiopia

Biruhalem Taye;Mirutse Giday;Abebe Animut;Jemal Seid

【期刊名称】《亚太热带生物医学杂志（英文版）》 【年(卷),期】2011(000)005

【摘要】Objective: To evaluate the activity of selected Ethiopian medicinal plants traditionally used for wound treatment against wound-causing bacteria. Methods: Samples of medicinal plants (Achyranthes aspera,

Brucea

antidysenterica, Acokanthera

Datura

stramonium,

Croton

macrostachyus, schimperi, Phytolacca dodecandra,

Millettia ferruginea, and Solanum incanum) were extracted using absolute methanol and water and tested for their antimicrobial activities against clinical isolates and standard strains of wound-causing bacteria using agar well diffusion and micro titer plate methods. Results: Most of the plant extracts had antibacterial activities, among which Acokanthera schimperi and Brucea antidysenterica inhibited growth of 100% and 35% of the test organisms, respectively. Methanolic extracts had higher activities compared with their corresponding aqueous extracts. The most susceptible organism to the extracts was Streptococcuspyogens while the most resistant were Escherichia coli and Proteus vulgaris. Conclusions: This finding justifies the use of the plants in wound healing