β-连环蛋白和膜突蛋白在胆囊癌中的表达及其意义
董星;董海峰;梁马可;赵龙栓
【期刊名称】《中国实用医刊》 【年(卷),期】2013(040)012
【摘要】Objective To investigate the expression and significance of β-catenin and moesin in gallbladder carcinoma.Methods The expression of β-catenin and moesin were examined by immunohistochemical analysis in 40 cases of gallbladder carcinoma and 15 cases of chronic cholecystitis and discuss its significance.Results The difference of the positive expression rate of β-catenin and moesin between gallbladder carcinoma and chronic cholecystitis was statistically significant (P ＜ 0.05).The difference of the positive expression rate of β-catenin in age,degree of differentiation,nevin staging,invasion depth in gallbladder carcinoma was statistically significant (P ＜ 0.05).The difference of the positive expression rate of moesin in degree of differentiation,nevin staging,invasion depth in gallbladder carcinoma was statistically significant (P ＜ 0.05).Conclusions ①Moesin and β-catenin can be used as an indicator to indentify malignant and benign.②The high expression of moesin and β-catenin in gallbladder cancer are associated with clinical stage,degree of differentiation,depth of invasion,and they can provide prognosis.%目的 探讨β-连环蛋白和膜突蛋白在胆囊癌、慢性胆囊炎组织中的表达并探讨其临床意义.方法 应用免疫组化法检测β-连环蛋白和膜突
β-连环蛋白和膜突蛋白在胆囊癌中的表达及其意义
