Antidiabetic and hypolipidemic activities of Kigelia pinnata flowers extract in streptozot

Antidiabetic and hypolipidemic activities of Kigelia pinnata flowers extract in streptozotocin induced

diabetic rats

Kumar S;Kumar V;Prakash OM

【期刊名称】《亚太热带生物医学杂志（英文版）》 【年(卷),期】2012(000)007

【摘要】Objective:To evaluate antidiabetic and hypolipidemic activities of Kigelia pinnata methanolic flowers extract in streptozotocin (STZ) induced diabetic wistar rat. Methods: Rats were made diabetic by a single dose of STZ at 60 mg/kg body weight i.p. The blood glucose level was checked before and 72 h after STZ injection to confirm the development of diabetes. The flower extract and glibenclamide were administered orally at the doses of 250 and 500 mg/kg body weight for 21 days. Results:Daily oral treatment with the extract and standard drug for 21 days significantly reduced blood glucose, serum cholesterol and triglycerides levels. High density lipoprotein-cholesterol level was found to be improved (P<0.01) as compared to diabetic control group. Conclusions:It is concluded that Kigellia pinnata flowers extract have significant antidiabetic and hypolipidemic effect. 【总页数】4页(543-546) 【关键词】

【作者】Kumar S;Kumar V;Prakash OM

【作者单位】Institute of Pharmaceutical Sciences, Kurukshetra University, Haryana, India;Institute of Pharmaceutical Sciences, Kurukshetra University, Haryana, India;Institute of Pharmaceutical Sciences, Kurukshetra University, Haryana, India 【正文语种】英文 【中图分类】 【文献来源】

https://www.zhangqiaokeyan.com/academic-journal-cn_asia-pacific-tropical-biomedical-journal-english_thesis/0201254091122.html 【相关文献】

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