“亚临床”2型糖尿病肾病患者尿血管紧张素原水平及相关
因素分析
杨笑云;常宝成;单春艳;徐延光;张祎;韩菲;王靖宇;许杰;郑妙艳
【期刊名称】《中华内分泌代谢杂志》 【年(卷),期】2015(031)005
【摘要】Objective To evaluate the level and related factors of urinary angiotensinogen
in
patients
with
\
diabetic
nephropathy.Methods (1) A total of 80 type 2 diabetic patients without angiotensin-converting enzyme inhibitor (ACEI) or angiotensin Ⅱ receptor blocker(ARB) treatment and hypertension were divided into 3 groups according to 24-hour urinary albuminuria and estimated glomerular filtration rate (eGFR):normoalbuminuria with normal glomerular filtration rate group [urinary microalbuminuria (UMA) ＜ 30 mg/24 h,90 ≤ eGFR ＜ 120 ml · min-1 · (1.73 m2)-1,NC group,n =28],normoalbuminuria with glomerular hyperfiltration group[UMA＜30 mg/24
h,eGFR≥
120
ml
·
min-1
·
(1.73
m2)-1,SDN
group,n=36],microalbuminuria group[30 h≤UMA＜300 mg/24 h,90 ≤eGFR＜120 ml · min-1 · (1.73 m2) 1,EDN group,n =16].The levels of urinary angiotensinogen among various groups were compared.(2)The levels
of
urine
retinol
binding
protein
(RBP),N-acetyl-β-D-
glucosaminadase,α-galactosidase,and β2-microglobubin were used to evaluate the renal tubular function.Then all the patients were divided
“亚临床”2型糖尿病肾病患者尿血管紧张素原水平及相关因素分析
