Antioxidant and anti-inflammatory potential of the aqueous extract and polysaccharide frac

Antioxidant and anti-inflammatory potential of the aqueous extract and polysaccharide fraction from brown marine macroalgae Padina sp. from Gulf of

Mannar of Peninsular India

Kajal Chakraborty

【期刊名称】《海岸生命医学杂志（英文版）》 【年(卷),期】2013(000)001

【摘要】Objective: To evaluate the antioxidant and anti-inflammatory potential of the aqueous extract and polysaccharide fraction from two brown marine macroalga, Padina gymnospora (P.gymnospora ) and Padina tetrastomatica (P. tetrastomatica) harvested from Gulf of Mannar of peninsular India.Methods:The antioxidant activity was evaluated using different in vitro systems, viz., 1,1-diphenyl-2-picrylhydrazyl (DPPH),

2,

2′-azino-bis-3ethylbenzothiozoline-6-sulfonic

acid

diammonium salt (ABTS), H2O2/ HO. radical scavenging, Fe2+ ion chelating ability, and reducing potential. Folin–Ciocalteu method was used to determine the total phenolic content, and the results were expressed as mg of gallic acid equivalents (GE). Thiobarbituric acid-reactive substance formation inhibition assay was employed to assess the ability of the samples to inhibit lipid oxidation in a model system. COXI and LOXV inhibition assays were employed to assess the anti-inflammatory potential of aqueous extract and polysaccharide