多模式MRI指导下不同时间窗脑梗死静脉溶栓血管再通临
床研究
陈翠荣;白青科;赵振国;赵晓晖;隋海晶;沈健;陆练军
【期刊名称】《脑与神经疾病杂志》 【年(卷),期】2017(025)006
【摘要】Objective To explore the cerebral artery recanalization and its influence on prognosis after multi-mode MRI based rt-PA intravenous thrombolysis in patients with stroke in different therapy time window. Method With the emergent brain MRI scaning who had been diagnosed as cerebral infarction within 12 hours of acute stroke symptom onset,one hundred and tweenty six cases were confirmed according with the standard of thrombolysis. Before treatment,MRA scaning of ninety-five cases showed that vascular TIMI grade were 2 grades or less,including sixty-four cases in group of within 4.5 hours, thirty-one cases in group of within 4.5~12 hours.Observe the artery recanalization of the two groups and study the relationship between artery recanalization and the prognosis. Results 24h after treatment,repetitive cranial MRA showed that vessel re-flowing was seen in forty-two cases within 4.5 hours group(42/64,65.62%)and nineteen cases within 4.5~12 hours group(19/31,61.29%).There were no significant difference between two groups in the rate of vascular thrombolytic recanalization. Recanalization was closely related to the location of cerebral