降纤酶联合抗血小板聚集药治疗急性缺血性脑卒中的疗效
分析
赵清
【期刊名称】《医学信息》 【年(卷),期】2014(000)023
【摘要】Objective To investigate the ef ect and safety of Defibrase combined with Aspirin in the treatment of acute ischemic stroke.Methods 88 patients with acute ischemic stroke were enrol ed in the study and al the patients were divided into three groups:Aspirin group,n=20),Defibrase group (B group,n=32)and Aspirin combined with Defibrase group (A+B group,n=36).Platelet count,platelet aggregation test (PAgT),fibrinogen ,High shear stress、Hematocrit coagulation studies (PT, APTT, INR),TXB2, National Institutes of Health Stroke Scale (NIHSS)and Modified Barthel Index (MBI)were measured or assessed before and after treatment ,respectively.Hemorrhage rate (including brain
and
other
organs)as
one
of
complication
was
also
investigated.Results After treatments,A combined with B group showed the strongest inhibition of platelet aggregation among the three groups ( <0.05).TXB2 level in A group and A combined with B group was significantly lower than that in B group ( <0.05).Plasma fibrinogen level and high sheer rate were decreased significantly in B group and A combined with B group compared with A group ( <0.05,
降纤酶联合抗血小板聚集药治疗急性缺血性脑卒中的疗效分析
