Comparison of antioxidant capacity and α-glucosidase inhibitory activity between bitter m

Comparison of antioxidant capacity and α-glucosidase inhibitory activity between bitter melon(Momardica charanti) fruit and leaf extract

Eun-Sun Hwang;

【期刊名称】《亚太热带生物医学杂志：英文版》 【年(卷),期】2018(000)004 【摘要】Objective:To

compare

the

physiologically

active

substances,antioxidant and anti diabetic activities in vitro of bitter melon fruit and leaf extract.Methods:Total polyphenol and flavonoid contents were measured using spectrophotometrically by gallic acid and catechin standard curves,respectively.The radical-scavenging potential of bitter melon fruit and leaf extract were measured by DPPH,ABTS and hydroxyl radical scavenging ability and reducing power and

anti-diabetic

ability

was

evaluated

byα-glucosidase

activity.Results:It was confirmed that the bitter melon leaf contained more total polyphenols and flavonoidsthan bitter melon fruits.Bitter melon leaf extract contained 2.8-fold and 4.9-fold higher total polyphenols and flavonoids than bitter melon fruits,respectively.The DPPH radical scavenging activity of bitter melon leaf was 5.81-and 5.70-fold higherthan that of the bitter melon frui,based on200μg/mL and 400μg/mL

of

the

extract,respectively.In

ABTS,hydroxyl

radical

scavenging ability and reducing power,the bitter melon leaf extract all