肝细胞癌患者根治性切除术后的预后因素分析
唐涛;廖锐;李静;杜成友
【期刊名称】《中华外科杂志》 【年(卷),期】2016(054)006
【摘要】Objective To explore the prognostic factors of patients with hepatocellular carcinoma(HCC) after radical resection.Methods From June 2006 to November 2009,preoperative peripheral blood and the clinicopathological data of 208 patients with HCC after curative resection treated in Department of Hepatobiliary Surgery,the First Affiliated Hospital of Chongqing Medical University,were collected and analyzed,including 173 male and 35 female patients with mean age of 53 years.Univariate analyses were applied by the Kaplan-Meier method,and then,significant clinical factors were used for further multivariate analyses by Cox proportional hazard regression model.The patients were divided into low-lymphocyte-monocyte ratio (MLR) group (MLR ≤ 1.2) and high-MLR group (MLR > 1.2) according to preoperative MLR.Results The enrolled 208 patients with median overall survival time for 38 months (1.5-82.2 months),median recurrence-free survival time for 36 months(1.0-82.0 months).Univariate analyses revealed
alanine
aminotransferase,serum
albumin,tumor
differentiation,tumor size,TNM stage and clinical stages and MLR might affect the prognosis significantly (all P < 0.05),and multiple analyses
肝细胞癌患者根治性切除术后的预后因素分析
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