小剂量 rt-PA 静脉溶栓治疗急性脑梗死的临床观察
赵惠荣;元小冬;郭晶;王燕玲
【期刊名称】《河北联合大学学报（医学版）》 【年(卷),期】2014(000)001
【摘要】Objective To evaluate the efficacy and safety of low dose rt -PA in the early treatment of the patients with acute cerebral infarction.Methods 30 patients within 6 hours from the onset of stroke were divided into 2 groups, thrombolytic group(16 cases)and control group(14cases).Patients in thrombolytic group received rt -PA 40mg, patients in control group did not receive thrombolytic therapy .NIHSS and Barthel Index ( BI) were used to evaluate the recovery of neurological functions after rt -PA 2 , 24 hours and 10 days.Cerebral CT were also reexamined .Results The scores of NIHSS after treatment were significantly better than before treatment in the both groups , and the improvement in the thrombolytic group was much greater than control group .The effec-tive rate was higher in thrombolytic group than in control group , There was significant difference between two groups (75%, 50%, P <0.05).There was a patient with gingival bleeding in thrombolytic group .There was no cerebral hemorrhagic complication and mortality in two groups .Conclusion For the individuals with acute cerebral infarction low dose rt -PA thrombolysis was effective and safe within 6h from the symptom onset in case of strict control .It is better
小剂量 rt-PA 静脉溶栓治疗急性脑梗死的临床观察
