ABO血型不相容肾移植的现状与进展
寻辉;王毅
【期刊名称】《中国社区医师》 【年(卷),期】2015(000)008
【摘要】Increasing the number of organ donor is still a huge obstacle for ABO incompatible transplantation.Both the antibody of anti blood type and anti donor HLA antibody can lead to hyperacute rejection and shift loss of plant.The ABO incompatible transplantation confirmed that early desensitization program can reduce the risk of rejection reaction.The reduction in blood B cell technology has replaced the resection of the spleen,and also overcomes the shortcomings of spleen resection.Plasmapheresis can greatly reduced the titer of plasma antibody,and has obtained the good effect of transplantation.The following new immunosuppressive scheme reduces the occurrence of early shift loss of function and the early rejection of plant,so as to improve the long-term graft survival ability.Therefore,ABO incompatible kidney transplantation can be widely used,especially in expaned the scope of donor and reduce transplant waiting time etc.%目的:增加活体器官供者的数量仍然是 ABO 血型不相容移植一个巨大的障碍。并且抗血型抗体和抗供者HLA抗体都可以导致超急性排斥反应与移植物失功的发生。在ABO血型不相容肾移植中证实可以通过早期的脱敏方案来降低这种早期排斥反应发生的风险。通过减少血液中的B细胞的技术已经代替了脾切术,且克服了