单肺与双肺移植治疗特发性肺间质纤维化的临床研究
孙敏;李慧星;谢于峰;徐辉;刘峰;陈静瑜
【期刊名称】《中华结核和呼吸杂志》 【年(卷),期】2016(039)006
【摘要】Objective To compare outcomes after single and bilateral lung transplantation in patients with idiopathic pulmonary fibrosis (IPF).Methods
104
patients
with
IPF
who
underwent
lung
transplantation at Wuxi People' s Hospital from January 2008 to February 2015 were evaluated.Recipients were divided into single lung transplantation
(STL)group(41
group
cases)and (63
bilateral
lung
transplantation(BLT) cases).Preoperative outcomes,postoperative
characteristics,postoperative
complications,functional outcomes,survival and causes of death between the two groups were analyzed retrospectively.The patients were followed up by letter,call and outpatient visit.Results Preoperative characteristics:The SLT group were significantly older (P < 0.05),and had significantly higher systolic (P < 0.05) pulmonary artery pressures than the BLT group.Postoperative outcomes:The intraoperative blood loss of SLT group as significantly less than BLT group (P < 0.05).The cold ischemic time of SLT group as significantly shorter than BLT group (P < 0.05).The BLT group was significantly more frequently required extracorporeal membrane oxygenation (ECMO) support than SLT group