APRI、AAR对肝硬化食管静脉曲张的诊断价值
冯洁;潘存伟;黄成军
【期刊名称】《现代消化及介入诊疗》 【年(卷),期】2013(000)003
【摘要】目的探讨谷草转氨酶/血小板比值指数(APRI)和谷草转氨酶-谷丙转氨酶比值(AAR)预测肝硬化食管静脉曲张的价值。方法肝硬化患者89例,均接受胃镜检查及血生化检验,应用受试者工作曲线评估APRI、AAR预测肝硬化患者食管静脉曲张存在的能力。结果静脉曲张组APRI为2.60±2.54,无静脉曲张组为0.77±0.68,两组相比有统计学意义(P<0.001);静脉曲张组AAR为1.27±0.53,无静脉曲张组为1.12±0.48,两组相比无统计学意义(P>0.05)。APRI预测食管静脉曲张的曲线下面积为0.84(0.75-0.93),最佳诊断界点为0.93,敏感度76.3%,特异度76.7%。APRI对轻度、中度、重度组食管静脉曲张预测的曲线下面积为0.66(0.47-0.85)、0.84(0.71-0.96)、0.92(0.84-0.99),最佳诊断值分别为0.7、0.93、1.02,灵敏度分别为54.5%、76.2%、88.9%,特异度为56.7%、76.7%、86.7%。结论 APRI可较好的预测食管静脉曲张的存在,APRI高值可提示重度静脉曲张。对于APRI高于0.93的患者,有必要进行胃镜检查。%Objective To explore the value of APRI and AAR for the presence of esophageal varices in patient with cirrhosis. Method Eighty-nine patients with liver cirrhosis were prospectively analyzed. Each pa-tient received endoscopy and serum biomarker examination. The receiver operating curve (ROC) was used to assess the relationship of these scores with the presence of esophageal varices.