血清尿酸在疑似冠心病患者中的临床价值评估
陶琴;陈君;张郁青
【期刊名称】《中西医结合心脑血管病杂志》 【年(卷),期】2014(000)011
【摘要】O bjective To explo re the clinica l va lue o f serum uric acid (SUA) in pa tients w ith co ronary artery disease (CAD). M e thods There w ere 229 consecutive pa tients w ith suspected CAD w ho had undergone co ronary ang iog raphy. Pa tients w ere divid-ed into non CAD g roup o r CAD g roup acco rding to the results o f co ronary artery stenosis. The serum uric acid leve l and o ther pa-ram e ters w ere com pared be tw een tw o g roups. Results There w ere 161 pa tients w ith CAD. SUA w as higher in pa tients w ith CAD com pared w ith cases w ithoutCAD ( 5.5m g /dL± 1.0m g /dL vs. 5.2m g /dL± 1.0m g /dL, P = 0.004). SUA w as associa ted w ith signif-icantly severity o fCAD ( P = 0.002). After adjusting fo r significant confounding facto rs including age, diabe tes, sm oking, cho lestero l, and m e tabo lic syndrom e (M S), SUA w as no t an independent risk facto r o f CAD ( P = 0.151). Based on a subg roup ana lysis, SUA w as m o re close ly associa ted w ith CAD in w om en than in m en, and in the highest quartile ( ≥ 6.4m g /dL) than in the first quartile (<4.8 m g /dL). how ever,these results w ere no t significant( P = 0.062,P = 0.075,respective ly). In m ultivaria te reg ression ana lysis, the m ost im po rtant de term inant o f SUA w as M S,
血清尿酸在疑似冠心病患者中的临床价值评估
