Human Sperm Chromosome Analysis—Study on Human Sperm Chromosome Mutagenesis Induced by C

Human Sperm Chromosome Analysis—Study on Human Sperm Chromosome Mutagenesis Induced

by Carbon Disulfide

LEJUN－YI;FUXIAO－MIN

【期刊名称】《生物医学与环境科学：英文版》 【年(卷),期】1996(009)001

【摘要】The aim of this study was to investigate the effect CS2 of on human sperm chromosomal aberration.The human sperm/hamster egg fusion techniquse was used to analyze 203 human sperm chromosome complement form 9 healthy volunteers.The incidence of numerical aberration was 1.0%,and that of structural chromosome aberration was 5.9% and total abnormalities was 6.9%.Structural aberrations consisted of

breaks,deletions,

centric

rings,fragments,and

chromatid

exchange.The results from high concentration group(10μmol·L-1 CS2)showed that the incidence of chromosomal aberration rate was significantly higher than that of the control group.The results indicate that high concentration of CS2 might directly cause mutatenesis f the germ cell.

【总页数】4页(P.37-40)

【关键词】人精子;染色体分析;染色体突变;二硫化碳;CS2 【作者】LEJUN－YI;FUXIAO－MIN 【

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