缺血性心律失常发生机制的研究进展
张莹茜
【期刊名称】《医学综述》 【年(卷),期】2011(017)021
【摘要】心肌缺血是诱发室速、室颤等恶性心律失常的主要原因,约占室速和室颤发生的65%,可导致心功能恶化、生活质量下降甚至猝死.但是,人们对缺血性心律失常机制的认识有限,因此,揭示缺血性心律失常的深层机制是抗心律失常研究领域的重点.近年研究发现,心室内外膜电活动分裂在缺血性心律失常的发生中起重要作用,这为临床预警和重症防治带来希望.êrdiac ischemia is the main cause of malignant arrhythmia such as ventricular tachycardia and ventricular
fibrillation,accounting
65%
incidence
of
ventricular
tachycardia and ventricular fibrillation, which causes heart function aggravation and life quality deterioration even sudden death. However,our knowledge about arrhythmias is limited. Hence,to explore the potential mechanisms is the focus of the research direction. Recent studies displayed that the electrical activity divorce between endocardium and epicardium played an important role in the generation of ischemic arrhythmia, which could bring along hopes for clinical
【总页数】4页(3210-3213)
【关键词】缺血性心律失常;机制;电活动分裂 【作者】张莹茜
缺血性心律失常发生机制的研究进展
