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Breathless cancer cells get fat on glutamine

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Breathless cancer cells get fat on glutamine

Dimitrios Anastasiou;Lewis C Cantley

【期刊名称】《细胞研究(英文版)》 【年(卷),期】2012(022)003

【摘要】Many cancer cells depend on glutamine as a fuel for proliferation,yet the mechanisms by which glutamine supports cancer metabolism are not fully understood.Two recent studies highlight an important role for glutamine in the synthesis of lipids and provide novel insights into how glutamine metabolism could be targeted for cancer therapy.

【总页数】4页(443-446) 【关键词】

【作者】Dimitrios Anastasiou;Lewis C Cantley

【作者单位】Beth Israel Deaconess Medical Center, Department of Medicine-Division of Signal Transduction; Department of Systems Biology,Harvard Medical School, Boston, MA 02115, USA;Beth Israel Deaconess Medical Center, Department of Medicine-Division of Signal Transduction; Department of Systems Biology,Harvard Medical School, Boston, MA 02115, USA 【正文语种】中文 【中图分类】 【相关文献】

Breathless cancer cells get fat on glutamine

BreathlesscancercellsgetfatonglutamineDimitriosAnastasiou;LewisCCantley【期刊名称】《细胞研究(英文版)》【年(卷),期】2012(022)003【摘要】Manycancercellsdependonglutamineasaf
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