不同羊膜腔穿刺适应证患者的染色体异常核型检出情况分
析
赵晓曦;谷孝月;武艾宁;于荣鑫
【期刊名称】《中华妇幼临床医学杂志（电子版）》 【年(卷),期】2014(000)006
【摘要】Objective To evaluate the detection rate of fetal chromosomal abnormalities in patients with different indications of amniocentesis and their genetic counseling.Methods From January 2009 and December 2013,a total of 520 pregnant women who underwent amniocentesis in the First Affiliate Hospital of Inner Mongolia University were included in the study.The study protocol was approved by the Ethical Review Board of Investigation in Human Being of First Affiliate Hospital of Inner Mongolia Medical University.Informed consent was obtained from each participants.The detection rates of fetal chromosomal abnormalities in patients
with
different
indications
of
amniocentesis
were
analyzed.Results Chromosomal abnormalities were observed in 4.42% (23/520 )of the samples.The detection rates of chromosomal abnormalities for each indication were 1.45% (3/206 )in advanced maternal age,3.1 5% (7/222 )in the increasing-risk maternal triple-marker screening test,12.72% (7/55 )in the abnormal ultrasound finding, 0 (0/29)for family history of chromosomal abnormality,80.00% (4/5)for the increasing-risk in the non-invasive prenatal testing, 66.67% (2/3 ) in
不同羊膜腔穿刺适应证患者的染色体异常核型检出情况分析
