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胸段食管鳞状上皮细胞癌淋巴结三野清扫的临床研究

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胸段食管鳞状上皮细胞癌淋巴结三野清扫的临床研究

胡成广;廉建红;任宾;张双平;王春利;郭石平

【期刊名称】《肿瘤研究与临床》 【年(卷),期】2009(021)008

【摘要】Objective To investigate the difference of complication incidence, death rate, quantity of lymphadeneetomy, lymphatic metastasis rate and long-term survival rate in thoracic squamons cell carcinoma of esophagus between three fields lymphadenectomy (3-FL) and traditional method. Methods Homoehronous 96 esophageal cancer patients were fractionated in two groups, 46 patients for 3-FL, the other 50 patients for traditional method. Results The average quantity of lymphadenectomy was 39.28 pieces per patient in 3-FL, and was significantly higher than 13.30 pieces per patient in traditional method (P <0.01). The rate of metastatic lymphatic nodes was 73.91%(34/46) in 3-FL patients, significantly higher than38.00%(19/50) in traditional method patients. For incidence of postoperative complications, recurrent laryngeal nerve damage and respiratory complication in 3-FL patients was significantly higher than patients in traditional method (P <0.05). The chest fluid obviously inereasod in 3-FL patients than in traditional method patients. There was significant contrast in 3-year survival rate between 3-FL patients and traditional method patients. Conclusion The there fields lymphadenectomy expand scope of

lymphdenectomy effectually, accurate the staging of thoracic esophageal carcinoma. At the same time, a lot of evidence was found in raising survival rate for 3-FL. Disadvantage of 3-FL was severe surgical trauma, high incidence of complication, and a long recovery time after operation.%目的 探讨胸段食管癌三野淋巴结清扫与传统术式在并发症发生率、死亡率、淋巴结清扫数量、淋巴结转移率和远期生存率等方面的差异,评价三野淋巴结清扫的优劣.方法 同期入组的96例食管癌患者随机分成两组,46例行食管癌淋巴结三野清扫(三野清扫组),另外50例接受传统术式(传统手术组).结果 三野清扫组扫除淋巴结39.28枚/例,显著高于传统手术组13.30枚/例(P<0.01);三野清扫组患者淋巴结阳性率73.91%(34/46),也明显高于传统手术组的38.00%(19/50);术后并发症发生率方面,喉返神经损伤和呼吸并发症三野清扫组显著高于传统手术组(P<0.05);三野清扫组术后胸腔积液引流量增多;三野清扫组3年生存率高于传统手术组(P<0.05).结论 三野清扫术有效地扩大了淋巴结的清扫范围,使食管癌的分期更加准确,同时在提高患者生存率方面也有大量的证据.但缺点是手术创伤大,并发症的发生率较高. 【总页数】3页(473-475)

【关键词】食管肿瘤;淋巴转移;手术后并发症 【作者】胡成广;廉建红;任宾;张双平;王春利;郭石平

【作者单位】030013,太原,山西省肿瘤医院胸外二病区;030013,太原,山西省肿瘤医院胸外二病区;030013,太原,山西省肿瘤医院胸外二病区;030013,太原,山西省肿瘤医院胸外二病区;030013,太原,山西省肿瘤医院胸外二病区;030013,太原,山西省肿瘤医院胸外二病区

【正文语种】中文 【中图分类】R73 【文献来源】

https://www.zhangqiaokeyan.com/academic-journal-cn_cancer-research-clinic_thesis/0201236930718.html 【相关文献】

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2.胸中段食管癌经颈胸腹三野淋巴结清扫与经左胸单切口二野淋巴结清扫的效果比较 [J], 张康; 张广敬; 崔宏伟; 刘计宽; 张鲁昌

3.472例胸段食管癌行颈、胸、腹三野淋巴结清扫术的临床研究 [J], 柳硕岩; 佘志廉; 朱坤寿

4.胸段食管癌淋巴结转移规律及其对淋巴结清扫方式的影响 [J], 李鹤成; 张亚伟; 相加庆

5.全腔镜下选择性食管癌颈胸腹三野淋巴结清扫与胸腹二野淋巴结清扫近期临床疗效的比对 [J], 韦海涛; 李丽; 王作培; 张锋; 胡宝利; 张海峰

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胸段食管鳞状上皮细胞癌淋巴结三野清扫的临床研究

胸段食管鳞状上皮细胞癌淋巴结三野清扫的临床研究胡成广;廉建红;任宾;张双平;王春利;郭石平【期刊名称】《肿瘤研究与临床》【年(卷),期】2009(021)008【摘要】ObjectiveToinvestigatethedifferenceofcomplicationincidence,deathrate,qu
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