坦索罗辛、索利那新治疗双J管致膀胱刺激症状的疗效观
察
胡尧;张先觉;李又空;周家杰;杨光华;丁坤;王建国
【期刊名称】《实用医学杂志》 【年(卷),期】2013(029)001
【摘要】目的:通过前瞻性研究方法探讨单用或联用坦索罗辛、索利那新治疗双J管所致膀胱刺激症状的疗效.方法:75例患者随机分入A、B、C、D组,A组19例,给予坦索罗辛口服治疗;B组18例,给予索利那新口服治疗:C组22例,给予坦索罗辛+索利那新口服治疗;D组16例,仅给予术后常规治疗.通过OAB症状评分问卷了解膀胱刺激症状严重程度,详细记录肉眼血尿、泌尿系感染及尿痛的发生率.结果:口服坦索罗辛或索利那新能够明显减轻双J管所引起的膀胱刺激症状,坦索罗辛的治疗作用强于索利那新,且两药联用疗效优于其中任何一种单药的疗效.坦索罗辛、索利那新及两药联用无法降低患者血尿及泌尿系感染的发生率,但是却可以降低尿痛的发生率,且两药联用的疗效强于单药的疗效.结论:坦索罗辛及索利那新能够有效地减轻双J管引起的膀胱刺激症状,并减少尿痛的发生,且两药联用疗效优于单药的使用.%Objective To explore the efficacy of tamsulosin and/or solifenacin in the treatment of overactive bladder symptoms caused by double-J ureteral stent via a prospective control study. Methods 75 patients were randomly devided into group A, B, C , or D. A total of 19 patients received tamsulosin alone (group A) , 18 patients received solifenacin alone (group B) , 22 patients receievd combination therapy with two agents (group C) , and 16 patients
坦索罗辛、索利那新治疗双J管致膀胱刺激症状的疗效观察
