妊娠合并全血细胞减少孕妇不良围产结局的危险因素分析
王雪燕;张超;梁梅英;张晓红;王建六;张霞
【期刊名称】《中华妇产科杂志》 【年(卷),期】2015(050)012
【摘要】Objective To explore the pregnancy outcomes of women with pancytopenia and the risk factors for the adverse perinatal outcomes.Methods A total of 106 pregnant women with pancytopenia were admitted to Peking University People's Hospital from Jan.2005 to Sep.2014.The clinical data and the pregnancy outcomes were reviewed retrospectively to investigate the risk factors for the adverse perinatal outcomes.Results (1)Eighty-four patients were found pancytopenia before pregnancy while 22 were found for the first time during pregnancy.Sixty-four patients were diagnosed as aplastic anemia;30 as myelodysplastic syndrome;2 as paroxysmal nocturnal hemoglobinuria;4 as hypersplenism,and 1 as anti-phospholipid syndrome.Diagnoses of the remaining 5 patients were uncertain.(2)Sixty-nine patients received at least one time blood transfusion before delivery.(3) As for the complications,nine women developed gestational diabetes;twenty-two suffered severe preeclampsia (SPE);two were diagnosed as anemic heart disease and three experienced respiratory tract infection.The postpartum blood loss ranged from 50 ml to 3 800 ml,with the median of 400 ml.And six women had the blood loss more than 1 000 ml.The