rSac3,a new member of Sac domain phosphoinositide phosphatases family
Lijun Li;Qi Wan
【期刊名称】《细胞研究（英文版）》 【年(卷),期】2007(017)011
【摘要】@@ Inositol phospholipids are concentrated in the cytosolic surface of membranes.Phosphatidylinositol(Ptdlns),the precursor of phosphoinositides,iS synthesized primarily in the endoplasmic reticulum.Reversible phosphorylation in the inositol ring of PtdIns at positions 3.4 and 5results in the generation of seven phOsphOinOsitide species:Ptdlns(3)P,PtdIns(4)P,PtdIns(5)P,PtdIns(3,4)P2,PtdIns(3,5)P2,PtdIns(4,5)P2,PtdIns(3,4,5)P3.Phosphoinositides can be rapidly interconverted from one species to another by strategically localized kinases and phosphatases[1]. 【总页数】3页(901-903) 【关键词】
【作者】Lijun Li;Qi Wan
【作者单位】Division of Fundamental Neurobiology,Toronto Western Research Institute,University Health Network,Toronto,Canada M5T 2S8;Department of Physiology,University of Toronto,Toronto,Canada M5S 1A8;Department of Surgery,University of Toronto,Toronto,Canada M5S 1A8;Division of Fundamental Neurobiology,Toronto Western
rSac3,a new member of Sac domain phosphoinositide phosphatases family
