Mass spectrometry analysis of melanoma related
O-glycans in sera
佚名
【期刊名称】《中国科学》 【年(卷),期】2010(000)004
【摘要】Glycomics comparison was carried out by screening melanoma serum biomarkers between C57 mice with and without B16 implanted. O-glycans were released from 10 μL sera by β-elimination, purified by Graphitized Carbon Cartridge Solid Phase Extraction (GCC-SPE) and analyzed by MALDI-QIT-TOF-MS. MS raw data were acquired and exported by Launchpad software. MATLAB was then applied for further data analysis. 10 Glycans were considered to have stable changes after B16 implantation and 5 of them were under structural analysis via MS/MS.
【总页数】5页(P.807-811)
【关键词】mass;spectrometry;glycomics;melanoma;biomarkers 【作者】佚名 【作者单位】; 【正文语种】英文 【中图分类】O6 【相关文献】
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Mass spectrometry analysis of melanoma related O-glycans in sera
