脑梗死患者微出血相关因素分析
李娟
【期刊名称】《中国医药》 【年(卷),期】2012(007)007
【摘要】目的 探讨脑梗死患者脑微出血一般临床因素及与同型半胱氨酸的关系.方法 选择我院2011年1-12月住院的脑梗死患者90例,经三维磁敏感加权成像检查判断是否合并脑微出血,,并对患者的临床特点及同型半胱氨酸等生化指标进行分析.比较有无合并脑微出血组相关危险因素及同型半胱氨酸等生化指标是否存在差异,并进行多因素回归分析.结果 脑微出血组36例,无脑微出血组54例.2组患者年龄、高血压病史、同型半胱氨酸含量差异有统计学意义( P=0.001,0.002,0.000).多因素回归分析显示,年龄(OR=1.041,95% CI为1.00~1.08;P =0.030)、高血压病史(OR=1.101,95%CI为0.56~1.99;P =0.004)、同型半胱氨酸含量(OR=1.20,95% CI为1.10~1.32;P =0.000)与脑微出血相关.结论 脑微出血与患者年龄、高血压病史、同型半胱氨酸含量相关.对于脑梗死患者合并脑微出血,更应该加强对血压、同型半胱氨酸的测定.%Objective To investigate the relation among cerebral micro-bleeds(CMBs),cerebral cardiovascular risk factors and homocysteine in patients
with
ischemic
stroke.Methods
Magnatic
Resonance
Imaging(MRI) was performed in 90 patients with acute ischemic stroke,which included susceptibility-weighted imaging.All patients received
cranial
magnetic
resonance
imaging
at
the
first
week.Homocysteine levels and other biochemical parameters were