他汀类药物的安全性风险评价
刘昌孝
【期刊名称】《现代药物与临床》 【年(卷),期】2014(000)008
【摘要】Statins are the most widely prescribed drug available pharmacotherapy for the management of high blood cholesterol levels virtually since their development. All of statin-drugs, such as atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin and simvastatin used for prevention of cardiovascular disease event. As all know, some of the patients taking statins experience adverse effects during therapy. Such as liver toxicity, muscle injury and increased cancer risk are the top adverse effects. Therefore, it is important to understand the risks involved with the drug class and individual statins. This paper analyzes and understands the risks on safety, adverse effects and toxicity of statins from published the clinical research data in the literatures. And it also introduced to evaluate information of use and risks of statins and the “2013 Guidelines on Statins Drop Cholesterol Targets” based on a four-year review of the evidence formulated by the American Heart Association and the American College of Cardiology.%他汀类药物是最广泛的可用药物治疗降低胆固醇水平，并控制其发展的处方药。所有的他汀类药物，如阿托伐他汀、氟伐他汀、洛伐他汀、匹伐他汀、普伐他汀、瑞舒伐他汀和辛伐他汀可用于心血管疾病事件的预防。众所周知，在治疗
他汀类药物的安全性风险评价
