动脉自旋标记在难治性颞叶内侧癫痫发作间期的应用
孙泓泓;吕长磊;白芝兰;张晓娜;师莉芳
【期刊名称】《实用放射学杂志》 【年(卷),期】2012(028)012
【摘要】Objective To determine whether pulsed ASL(PASL) MR] using flow-sensitive alternating inversion recovery) FAIR) could be a useful clinical tool to detect intcrictal temporal hypopcrfusion in mesial temporal lobe cpilcpsy(TLEl) ,thcn on the base of changes of cerebral blood flow(CBF) to determine the seizure focus. Methods 15 normal controls and 15 patients were studied by using a FAIR pcrfusion mode to measure the CBF of mesial temporal lobe. According to the vidco-clcctrocnccphalography ( VEEG) findings, the origin sides of seizure were obtained in all patients. Results Pcrfusion in control participants was ( 167. 95 ± 15. 30) mL/( 100 g · min) on the right and (169.64 ± 13.24) mL/( 100 g · min) on the left. In patients, mesial temporal lobe pcrfusion was (158.42 ± 9.09) mL/(100 g- min) on the ipsilatcral (affected) side and (170. 11±7. 67) mL/(100 g · min) on the contralatcral (unaffected) side. The blood flow measurements were significantly different in ipsilatcral versus contralatcral sides in patients. In control participants, the mean absolute asymmetry index was 2. 49 ± 2. 09. For the patients, mean absolute asymmetry index was 7. 20 ± 4. 21. The difference was statistically significant P = 0. 001 ). The coefficient of
动脉自旋标记在难治性颞叶内侧癫痫发作间期的应用
