临床肺科杂志2019年6月第24卷第6期977
CT引导下经皮肺穿刺并发气胸的影响因素分析
张海琴1
【摘要】目的分析
程齐俭1万欢英2
法回顾
2018年1月呼吸科行CT引导下经皮肺穿刺术的所有患者,按是否并发气胸分为两组,统计分析两组的临床 资料。结果共210例,男性148例、女性62例,年龄63(55 ,71)岁;病灶直径3. 1 (2,4. 7) cm, CT值35(24, 46) Hu;病灶外缘离穿刺点距离1. 05 & 0. 2,2. 3 ) cm;术后病理学诊断为肺恶性肿瘤71 % $炎性病变29%。并发 气胸者47例(22. 4% ),肺压缩最大面积约80%,1例合并皮下气肿,均治疗后康复,时间1 -5天。卡方分析 示,肺部病灶密度不均、病灶外缘离穿刺点距离大于、等于3cm或伴有肺气肿、肺大疱的患者,术后气胸发生 率较高(! <0. 05),气胸与性别等其他因素无明显关联;L〇gls@回归显示,病灶密度不均、病灶外缘离穿刺点 距离大于等于3cm、存在肺气肿、肺大疱,为术后并发气胸的危险因素(!< 0.05),相对危险度(OR)分别为 6. 264、2. 971、8. 444。结论气胸是CT引导下经皮肺穿刺的常见并发症;病灶密度不均、病灶外缘离穿刺点 距离大于等于3cm或存在肺气肿、肺大疱的患者,术后气胸的发生率显著增高。
【关键词】气胸;经皮肺穿刺;并发症Analysis of the influencing factors of pneumothorax after CT-guided percutaneous lung punctureZHANG Hai-qin,CHENG Qi-jicrn,WAN Huan-ying Department of Pulmonary Disease,Ruijin Hospital North Affilia-ted to Shanghai Jiaotong University School of Medicine,Shanghai 201801,China
【Abstract】 Objective To analyze theprobability and influencingfactors of pneumothorax complicated withCT-guided percutaneous lung puncture. Metliods The clinical data of all patients who underwent CT-guided percutane-ous lung puncture in the department of pulmonary disease from August 2013 lyzed, and they were divided into two groups according to whetlier they were Results There were 210 cases,including 148 males and 62 females with an diameter was 3. 1 (2,4. 7) cm and CT value was 35 (24,46) Hu. The distancc between the outer edge of the lesion and the puncture point was 1. 05 cm (0. 2,2. 3). Postoperative pathological diagnosis was 71 % of pulmonary malig-nant tumor and 29% of inflammatory lesions. 47 patients (22. 4% ) were complicated with pneumothorax,the largest area of pulmonary compression was about 80%,and 1 patient was complicated with patients recovered after treatment for 1 -5 days. Chi-scjuare analysis showed that thie incidence of postoperative pneu-mothorax was higher in patients with uneven lung lesion density,distance of the lesion from puncture point greater than or equal to 3cm, or patients with emphysema and pulmonary bullae ( P < 0. 05 ). Pneumothorax was not
doi: 10. 3969/j. issn. 1009 - 6663.2019. 06.003作者单位:1201801上海,上海交通大学医学院附属瑞金医院北院呼吸科
2.200025上海,上海交通大学医学院附属瑞金医院呼吸与危重病学科上海市重中之重临床重点学科上海
交通大学医学院呼吸病研究所
通信作者:程齐检,E-mail % chengqijian@aliyun. com
CT引导下经皮肺穿刺并发气胸的概率及影响因素。方2013年8月至
to Janua
complicaaverage
subcutan
对于COPD患者病情控制具有重要意义。
参考文献
[1] 李娜,霍建民? AECOPD预后影响因素研究进展)J* ?临床肺科
杂志,2018,23(7)29 -1333.
[2] 中华医学会呼吸病学分会慢性阻塞性肺疾病学组.慢性阻塞
性肺疾病诊治指南(2013年修订版)[S]?中华结核和呼吸杂 志,2013,36(4)%5 -264.[3] 王晓龙,周向东?慢性气道炎症黏液高分泌的分子机制[J]?国
际呼吸杂志,2〇〇6,26(10)u5 -757.
[4] 徐晓艳,周向东? COPD患者气道中性粒细胞弹力酶活性与肺
组织Elafin表达的关系及意义[J ].临床肺科杂志,2005,10(I) 3 -34.[5] GUYOT N,BUTLER M W,MCNALLY P,et al. Elafin,an elastase
-specific inhibitor,is cleaved by its cognate enzyme neutrophil elastaseinsputumfromindividuals'withcysticfibrosis[J].JBiolChem,2008,283(47) 2377 -32385.[6] 杨捷,周向东.慢性炎症气道粘液高分泌治疗药物研究进展
[J] ?中国药业,2004,13(4)1 -33.
[收稿日期
%2018 -12 -06]