磁共振动态磁敏感增强和DWI在鉴别脑肿瘤复发与放射性
坏死中的应用
韩芳;伍建林;张明;梁珊珊;敦旺欢;田思淼;王静石
【期刊名称】《中华转移性肿瘤杂志》 【年(卷),期】2024(001)003
【摘要】Objective The study was designed to compare the diagnostic accuracy of diffusion weighted imaging (DWI) with dynamic susceptibility-contrast (DSC) MRI in differentiating radiation necrosis from tumor recurrence in patients with brain tumor.Methods Relevant Studies about DWI and DSC in differentiating radiation necrosis from tumor recurrence in PubMed,EMBASE,Web of Science and Cochrane databases were searched for relevant articles up to November 2017.Two authors independently selected and screened studies that met the inclusion criteria.Pooled SEN,SPE),positive likelihood ratio (PLR),negative likelihood ratio (NLR),diagnostic odds ratio (DOR),and area under the curve (AUC) were calculated.Results A total of 14 surveys that investigated DSC or DWI for differentiating radiation necrosis from tumor recurrence were included.The current study found that pooled sensitivity and specificity of DSC in differentiating radiation necrosis from tumor recurrence were 0.88(95% CI:0.82-0.93) and 0.85(95%CI:0.77-0.91),respectively.The same measures for DWI were 0.84(95% CI:0.77-0.89) and 0.84 (95 % CI:0.73-0.90),respectively.Moreover,DSC