左氧氟沙星联合三联疗法治疗幽门螺旋杆菌相关性胃溃疡
的临床研究
王岩;邢煜;王经元
【期刊名称】《现代药物与临床》 【年(卷),期】2016(031)004
【摘要】Objective To study the efficacy of Levofloxacin Lactate Tablets combined with triple therapy in treatment of Helicobacter pylori associated gastric ulcer. Methods Patients (134 cases) with H. pylori associated gastric ulcer in The People’s Hospital of Liaoning Province from June 2014 to Jun 2015 were randomly divided into control (n = 67 ) and treatment (n = 67 ) groups. Patients in the control group were treated with triple therapy, and the patients in the treatment group were po administered with Levofloxacin Lactate Tablets from 6th day on the basis of the control group, 200 mg/time, once daily. The patients in two groups were treated for 10 d. After treatment, the efficacy and H. pylori eradication rate were evaluated, and inflammatory factors in serum and incidence rate of adverse reaction in two groups were compared. Results After treatment, H. pylori eradication rate in the treatment group (83.6%) was higher than that (52.2%) of the control group, and the efficacies in the control and treatment groups were 79.1% and 94.0%, respectively, and there were differences between two groups (P < 0.05). After treatment, levels of IL-6 and IL-17 in serum in two
左氧氟沙星联合三联疗法治疗幽门螺旋杆菌相关性胃溃疡的临床研究
