自体骨髓干细胞移植治疗急性心肌梗死临床研究
张奇峰;钟志雄;李斌;李存仁;张鹏飞;叶卓联;古献芳
【期刊名称】《中国医学前沿杂志（电子版）》 【年(卷),期】2014(000)006
【摘要】Objective To explore the effect of autologous bone marrow stem cells transplantation in treatment of acute myocardial infarction. Method 38 cases patients with acute myocardial infarction, and the inclusion criteria for acute myocardial infarction comply with the WHO diagnostic criteria. Patients were randomly divided into the bone marrow stem cell transplantation group (PCI+stem cell transplant, n=18) and the control group (only PCI, n = 20). Patients were regular use of aspirin, clopidogrel, atorvastatin, beta blockers, angiotensin converting enzyme inhibitors, such as drugs, merge the routine use of diuretics in patients with heart failure. Transplantation group were recorded in infarct related blood vessels PCI for stem cell transplantation. Compare the treatment effect. Result The observation group after 3 months, 6 months according to the clinical evaluation of cardiac function NYHA classiifcation and walking test results improved signiifcantly (P < 0.05);and there was no significant difference before treatment, the control group (P>0.05). After follow-up,two groups of patients with left ventricular end-diastolic diameter (LVDD) no obvious change compared with the preoperative, P > 0.05). All patients in preoperative, 3, 6
自体骨髓干细胞移植治疗急性心肌梗死临床研究
