【VIP专享】TOYOPEARL填料实际应用产品的清单(中英文)

1. TOYOPEARL APPLICATION IN LOW MW COMPOUNDS / TOYOPEARL在低分子化合物中的应用Target Molecule

Inorganic Ion / 无机离子Li+, Na+ / 锂、钠离子

Platimun group metal / 铂类金属Zn complex / 锌复合物

Low MW Compound / 低分子化合物Detergent / 去垢剂

alkylporphyrin / 烷基卟啉Detergent / 去垢剂Detergent / 去垢剂

Pyrroro-quinoline quinone / 吡咯喹啉苯醌Active Low MW Compounds / 活性低分子化合物Acakyphidins

Anthocyanin / 花青素Anthraquinone / 蒽醌Black vinegor

Catechin / 儿茶酚Chestanin

Digoxin / 异羟洋地黄毒苷,地高辛EpigarocatechinFlavan / 黄烷

Flavonoid glycoside / 类黄酮配糖类Galloylarbutin

Isoflavonoid / 异黄酮

Ouabain / 乌本（箭毒）苷

plant growth hormone / 植物生长激素Polyphenol / 多酚

Proanthocyanidin oligomer / 花色素低聚物ProcyanidineTannin / 丹宁酸Theaflavin

ToyopearlHW-40FHW-40CHW-40F

Comment

patent

HW-40FHW-40Butyl-650Butyl-400HW-40S

Methanol30 L scaleSpecial gradepatent

HW-40HW-40FDEAE-650CHW-50FHW-40HW-40FHW-40HW-40CHW-40HW-40FHW-40HW-40

HW-40C, ECHW-40FHW-40S, FHW-40HW-40

patentWater50 % methanol50% methanol

Methanol:water = 70:3050% methanol

patent

patent

Active Pharmaceutical Ingredient (API), Traditional Chinese Medicine (TCM)活性药物成分（API），中药（TCM）

HW-40CAliphatic acid amide / 脂肪族酰胺

Anti-complementary acidic heteroglycanDEAE-650C

HW-55Antidiabetic compound / 抗糖尿病化合物

CM-650MAntiemetic agent / 止吐剂

HW-40Antifungal compound / 抗真菌化合物

Antifungal compound (Azoxy compound)HW-40

HW-40FAnti-oxidant phenolic compounds / 抗氧化酚类化合物

patent

patentpatentpatent

ToyopearlTarget Molecule

Active Pharmaceutical Ingredient (API), Traditional Chinese Medicine (TCM)活性药物成分（API），中药（TCM）

HW-40FAntitumor substance / 抗癌化合物

AstragalineHW-40C

HW-40CCarcinogen promotion inhibitor/ 致癌物质抑制促进剂

HW-40Extract from pine needle / 松针抽提物

HW-55F, DEAE-650Ginseng fraction / 人参,高丽参组分

HW-40FHair growth stimulant / 头发生长刺激物

LimonoidHW-40Nematode-antagonistic compoundHW-40

HW-40COxacillin / 苯甲异噁唑青霉素（新青二）

Phenylethanoid glycosideHW-40Taxifolin apiosideHW-40FAntibiotics / 抗生素##STR5##

Actinomycin / 放射菌素Anthracycline / Antibiotics / 抗生素Chloropolysporin C / Cirratiomycin A / DO-248-A, B

Mureidomycin A-D / Trieinomycin /

Food Additives / 食品添加剂Yellow pigment / 黄色素

Riboflavin monoglucoside / 核黄素配糖物单体Synthetic Polymer / 合成树脂Polyethylene glycol / 聚乙二醇Polyethylene glycol / 聚乙二醇

Comment

patentpatent

patent

methanol/water, step gradient

HW-40HW-40CHW-40CM-650CHW-40FHW-40FHW-50CHW-40

HW-40, DEAE-650

patent

Hexan: Ethylacetate:Aceticacid:Methanol:Water =100:30:20:20:4patent300 L scalepatentWaterpatentpatent

HW-40FHW-40Fpatentpatent

HW-40SButyl-650Mwaterpatent

2. TOYOPEARL APPLICATION IN AMINO, PEPTIDE, PROTEIN AND VACCINE / TOYOPEARL在氨基酸, 多肽, 蛋白质及疫苗中的应用Target Molecule

Amino Acid / 氨基酸

hydroxy proline / 羟基脯氨酸Peptide / 多肽

Aprotinin / 胰蛋白酶抑制剂（抑肽酶）Insulin / 胰岛素Insulin / 胰岛素

Lactoferricin / 乳铁传递肽

Parathyroid hormone / 甲状旁腺（激）素Peptide / 多肽

Peptide digest / 多肽水解物Peptides (3 types) / 多肽（3种）r-Insulin / r胰岛素

Sardines hydrolysate / 沙丁鱼水解产物Growth Factor / 生长因子

Epidermal growth factor (GF) / 表皮生长因子Epidermal growth factor (GF) / 表皮生长因子EPO binding protein /

Erythropoietin (EPO) / （促）红细胞生成素Erythropoietin (EPO) / （促）红细胞生成素G-CSF conjugate / 粒细胞集落刺激因子Growth Factor / 生长因子Growth factor-7 / 生长因子

human growth hormone / 人生长激素

r-human growth hormone (GH) / r人生长激素Inerleukin-10 / 白细胞介素-10Inerleukin-6 / 白细胞介素-6

Insulin-like growth factor / 类胰岛生长因子Interferon (feline) / 干扰素（猫科动物）Interferon Alpha / α干扰素Interferon Alpha / α干扰素Interferon Alpha / α干扰素Interferon Beta / β干扰素Interferon Epsilon / ε干扰素

Interferon PEGylated / PEG化干扰素Interleukin-2 / 白细胞介素-2Interleukin-8 / 白细胞介素-8

HW-55F

SP-550C, MegaCap II SP-550ECEther-5PW, Phenyl-5PW (650)CM-650M, Butyl-650MCM-650SCM-650MHW-40FSP-650DEAE-650MHW-40

3 M guanidine-HCl + 2.4 Mformic acid

ToyopearlDEAE-650S

Commentpatent

patentpatent500 L scale

0.2 M carbonate buffer (pH10 L scale1230 L scale

0.2 M ammonium acetate (pH5)

Phenyl-5PWSP-650MPhenyl-650

Butyl-650C, AF-Blue HC 650MButyl-650S

DEAE-650M, Butyl-650MHW-55FButyl-650Phenyl-650M

Butyl-650, Phenyl-5PWButyl-650M

Butyl-650M, AF-Heparin HC-650MSP-550C, Butyl-650M, Phenyl-650AF-Red 650MButyl-650Phenyl-650S

CM-650M, Butyl-650MButyl-650Butyl-65-Phenyl-650M

Phenyl-5PW, Ether-5PWHW-55

patentpatent

60 L and 30 L scale,respectivelypatentpatentpatent

patentpatentpatentpatentpatentpatentpatent50 L scalepatentpatent

Target Molecule

Growth Factor / 生长因子

M-CSF 223 protein / M-CSF 223 蛋白Neutrophins /TGF Beta-family /

Tumor Necrosis Factor (TNF) / 肿瘤坏疽因子Other proteins / 其他蛋白质

Allergen (mite) / 变态反应原（螨类）Antibody (monoclonal) / 抗体（单抗）Beta-Galactosidase / β牛乳糖Carboxyl peptidase / 羧基肽酶

Dihydrofolate reductase / 二氢叶酸还原酶Elastase inhibitor / 弹性蛋白酶阻断剂Fc-fusion protein /

Haemoglobin / 血色素、血红蛋白

HCV serine-proteinase / HCV丝氨酸蛋白酶Hirudin / 水蛭素

Histidinol dehydrogenase / 组氨醇脱氢酶Lactoferrin / 乳铁传递蛋白Proteinase K, Aminopeptidase K/ 蛋白酶K、氨基肽酶K

Removal of virus from biopharmaceuticals/ 生物制药中病毒的除去Sphingomyerinase /

Superoxide Dismutase (SOD)/ 过氧化物歧化酶Urease / 脲酶、尿素酶Urease / 脲酶、尿素酶

Vaccine / 疫苗

Hepatitis B Vaccine / 乙肝疫苗

Hepatitis A Virus Vaccine / 甲肝疫苗Malaria immunogen and vaccine/ 疟疾免疫原和疫苗Adenovirus / 腺病毒Adenovirus / 腺病毒Retroviral vector /

ToyopearlPhenyl-650Phenyl-650MButyl-650HW-55F

Commentpatentpatentpatentpatent

DEAE-650, Butyl-650Phenyl-650M, Butyl-650MSP-650Butyl-650

DEAE-650, Butyl-650

DEAE-650, AF-Red 650M, HW-55Phenyl-650CAF-Chelate 650M

Methotrexate-AF-Tresyl-650MButyl-650DEAE-650CM-650CM-650

Butyl-650, Phenyl-650

Butyl-650, DEAE-5PW, Phenyl-5PWButyl-650M

HW-65

Butyl-650C, DEAE-650S

patentpatent50 Lpatentpatent

8 L, 5 L, and 5 L scalepatentpatentpatentpatentpatent40 L scalepatentpatentpatent15 L scalepatent

DEAE-650

DEAE-650M, HW-55S, HW-65SButyl-650, Ether-650SuperQ-650, G6000PWHW-40CSuperQ-650

50 L scalepatentpatentpatentpatentpatent

3. TOYOPEARL APPLICATION IN PLASMA PROTEIN / TOYOPEARL 在血浆蛋白质中的应用Target Molecule

Plasma Protein / 血浆蛋白Albumin / 血清（白）蛋白Albumin / 血清（白）蛋白Albumin / 血清（白）蛋白Albumin / 血清（白）蛋白

Alpha 1 acid glycoprotein / α1酸性糖蛋白Alpha 1 antitrypsin / α1抗胰岛素Antibody / 抗体Antibody / 抗体

Antibody / 抗体Antibody / 抗体Antibody / 抗体

Antithrombin III / 凝血酶 IIIAntithrombin III / 凝血酶 IIIAntitumor factor / 抗癌因子Enzyme / 酶

Factor IX / 九因子Factor IX / 九因子Factor VII / 七因子

Factor VIII / 八因子

Factor VIII/vWF / 八因子/vWFFactor VIII/vWF / 八因子/vWFFactor VIII/vWF / 八因子/vWFFactor XIII / 八因子IgA / 免疫球蛋白A

Name not disclosed / 未公开Name not disclosed / 未公开

r human albumin / r人血清白蛋白r human albumin / r人血清白蛋白r human albumin / r人血清白蛋白Thrombin / 凝血酶

Tissue plasminogen activator (rPA)/ 组织血浆酶原催化剂

Toyopearl

DEAE-650, QAE-550C, SuperQ-650M

QAE-550C, SP-650HW-50F

Phenyl-650, Butyl-650M,SuperButyl-550CSuperQ-650SuperQ-650GigaCap S

PPG-600M, Butyl-600M, Phenyl-650M

DEAE-5PW

SP-650C, Butyl-650SP-650, Butyl-650AF-Heparin HC 650M

AF-Chelate 650M, Butyl-650DEAE-650Affinity HW-65FDEAE-650M

QAE-550C, DEAE-650, SP-650DEAE-650, SuperQ-650, Butyl-650, Phenyl-650

DEAE-650M, AF-Heparin HCDEAE-650M

AF-Heparin HC 650MSP-550C, CM-650Butyl-650DEAE-650QAE-550CButyl-650MHW-50F

DEAE-650M, Butyl-650

DEAE-650, SuperQ-650, Butyl-650, Phenyl-650AF-Heparin HC 650MDEAE-650, Butyl-650

Comment

patent

patentpatent

10 L

25 L and 60 L, respectively

30 L and 10 L scale, respectivelypatentpatent

1000 L scalepatentpatent200 L scalepatentpatentpatentpatent500 L scale200 L scalepatentpatentpatent

50 L and 20 L scale, respectively