腹腔热灌注联合静脉化疗治疗晚期卵巢癌的疗效观察
岳丽娟;侯新丽;薛辉;薛玲;高翔;沈勇;袁亮;张晶晶;朱宏财
【期刊名称】《现代肿瘤医学》 【年(卷),期】2014(000)008
【摘要】Intraperitoneal hyperthermic chemotherapy(IHCT)has been used in the treatment of ovari-an cancer,to determine the efficacy of IHCT combined with intravenous chemotherapy in the treatment of advanced o-varian cancer. Methods:From 2008 to 2012,100 patients with advanced ovarian cancer were enrolled in a prospective nonrandomized study to undergo IHCT combined with intravenous chemotherapy. There were 60 cases in the treatment group,receiving intraperitoneal hyperthermal chemotherapy with DDP and intravenous chemotherapy with PTX. There were 40 cases in the control group,receiving intravenous chemotherapy with PTX and DDP. The ascites control rate and the main side effects were observed in the two groups. Results:The ascites control rate was 78. 3% in the treat-ment group and 42. 5% in the control group,with a significant difference between the two groups(P ﹤ 0. 01). The rates of the main side effects in the two groups were not significantly different(P ﹥ 0. 05). Conclusion:The
effect
of
IHCT
combined
with
intravenous
chemotherapy on advanced ovarian carcinoma is better than that of intravenous chemotherapy alone and is a well - tolerated,feasible,and
腹腔热灌注联合静脉化疗治疗晚期卵巢癌的疗效观察
