Should antiplatelet therapy be interrupted in drug eluting stent recipients throughout the

Should antiplatelet therapy be interrupted in drug

eluting stent recipients throughout the periendoscopic period? A very late stent thrombosis case re-port and review of the

literature

Peng DONG;Xin-Chun YANG;Su-Yan BIAN

【期刊名称】《老年心脏病学杂志（英文版）》 【年(卷),期】2014(000)003

【摘要】In-stent thrombosis after cessation of antiplatelet medications in patients with drug-eluting stents (DES) is a significant problem in medical practice, particularly in the perioperative period. We report a case of an 87-year-old man with a medical history of hypertension, coronary artery disease and chronic atrophic gastritis. Very late thrombosis of a sirolimus-eluting stent occurred 1207 days after implantation, seven months after discontinuation of clopidogrel, and the interruption of aspirin 13 days in preparation of an elective endoscopic

gastroin-testinal

procedure

presented

with

acute

myocardial infarction. The patient was treated with thrombectomy and successfully revascularized with superimposition of two sirolimus-eluting stents. Medications administered in the catheterization laboratory included low molecular weight heparin and nitroglycerin. Flow was defined as grade 2 according to the thrombolysis in

myocardial infarction scale. Electrocardio-gram after the procedure revealed persistent, but decreased, ST-segment elevation in the anterolateral leads. The patient recovered and was discharged on aspirin and clopidogrel indefinitely. There was no cardiac event during the two year follow-up period. This case underlines the importance of maintaining the balance of thrombosis and bleeding during perioperation of non-cardiac procedure and the possible need for continuation of aspirin therapy during periendoscopic procedures among patients with low bleeding risks who received DES. 【总页数】4页(274-277) 【关键词】

【作者】Peng DONG;Xin-Chun YANG;Su-Yan BIAN

【作者单位】Department of Cardiology, Capital Medical University, Chaoyang Hospital, Beijing 100053, China;Department of Cardiology, Capital Medical University, Chaoyang Hospital, Beijing 100053, China;Second Department of Geriatric Cardiology, General Hospital of the People’s Liberation Army, Beijing 100853, China 【正文语种】英文 【中图分类】 【文献来源】

https://www.zhangqiaokeyan.com/academic-journal-cn_journal-geriatric-cardiology_thesis/0201230768441.html

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