多药耐药基因产物及CerbB-2、ki-67在胃癌中的表达及
其临床病理学意义
韩军平;刘斌;孟晓燕;杨艳丽;苏勤军
【期刊名称】《现代肿瘤医学》 【年(卷),期】2011(019)011
【摘要】Objective: To investigate the expressions of Pg - p, GST - π , Topo - Ⅱ , cancer gene CerbB - 2, cell multiplication index ki - 67 and the clinical pathology significance in stomach cancer. Methods: Their expression was examined by immunohistorchemistry method. Results: No remarkable difference in the positive expressions of Pg- p, GST - tt were found with stomach cancer s Lauren divides, the pathology graduation and lymph node metastasis ( P ＞ 0. 05 ), but the depth of cancer infiltration had significance difference ( P ＜ 0. 05 ). No remarkable difference in the positive expressions of Topo - II were found with stomach tumor differentiation, and the lymph node metastasis ( P＞0. 05 ),but the stomach cancers Lauren divides had the significance difference ( P ＜0. 05 ). No remarkable difference in the positive expressions of CerbB - 2,ki -67 were found with stomach cancer's Lauren divides, pathology graduation and the depth of cancer infiltration ( P ＞0. 05 ) ,but lymph node metastasis had the significance difference ( P ＜0. 05 ). Conclusion: There are great meanings to judge the stomach cancer patient prognosis and clinical treatment by union
多药耐药基因产物及CerbB-2、ki-67在胃癌中的表达及其临床病理学意义
