Magnetic nanoparticle-based cancer
nanodiagnostics
Muhammad Zubair Yousaf;Yu Jing;Hou Yang-Long;Gao Song
【期刊名称】《中国物理:英文版》 【年(卷),期】2013(022)005
【摘要】Diagnosis facilitates the discovery of an impending disease.A complete and accurate treatment of cancer depends heavily on its early medical diagnosis.Cancer,one of the most fatal diseases world-wide,consistently
affects
a
larger
number
of
patients
each
year.Magnetism,a physical property arising from the motion of electrical charges,which causes attraction and repulsion between objects and does not involve radiation,has been under intense investigation for several years.Magnetic materials show great promise in the application of image contrast enhancement to accurately image and diagnose cancer.Chelating gadolinium (Gd Ⅲ) and magnetic nanoparticles (MNPs) have the prospect to pave the way for diagnosis,operative management,and adjuvant therapy of different kinds of cancers.The potential of MNP-based magnetic resonance (MR) contrast agents (CAs) now makes it possible to image portions of a tumor in parts of the body that would be unclear with the conventional magnetic resonance imaging (MRI).Multiple functionalities like variety of targeting ligands and image contrast enhancement have recently been added to the