TCT 和 HPV －DNA 联合检测在宫颈癌及癌前病变筛查中
的应用价值
熊炜;陈萰
【期刊名称】《中国计划生育和妇产科》 【年(卷),期】2015(000)012
【摘要】Objective To investigate the application value of union detection of thin -cytologic test ( TCT) and the high-risk human papilloma virus ( HPV)-DNA in screening for cervical cancer and precancerous lesions .Methods Clinical data of 653 women patients in Fifth Hospital in Wuhan from February 2013 to October 2013 were detected by HPV-DNA and TCT.The patients of TCT positive and HPV -DNA positive received pathological biopsy under colposcope .Results The sensitivity of HPV -DNA single detection was the highest , but the specificity , positive predictive value and the diagnosis coincidence rate was the lowest .The sensitivity and negative predictive value of TCT single detection was the lowest .The diagnostic accordance rate , positive predictive value and specificity of the union detection of TCT and HPV -DNA were significantly higher than that of TCT , HPV-DNA single test (P<0.05).Conclusion The union detection of TCT and HPV -DNA can improve the screening and early diagnosis rate of the cervical cancer and precancerous lesions .%目的：探讨液基薄层细胞检测技术（thin－cytologic test， TCT）和高危型人乳头瘤病毒（human papilloma
TCT 和 HPV -DNA 联合检测在宫颈癌及癌前病变筛查中的应用价值
