The Al-2-dependent regulator LsrR has a limited regulon in Salmonella Typhimurium

The Al-2-dependent regulator LsrR has a limited

regulon in Salmonella Typhimurium

Inge M Thijs;Sigrid CJ De Keersmaecker;Hui Zhao;Ami De Weerdt;Kristof Engelen;David De Coster;Geert Schoofs;Michael McClelland;Jos Vanderleyden;Kathleen Marchal

【期刊名称】《细胞研究（英文版）》 【年(卷),期】2010(020)008

【摘要】@@ Dear Editor,rnBacteria are able to communicate with each other through small, diffusible molecules. In some species,this type of communication has been linked to virulence.Therefore, bacterial cell-cell communication pathways have recently been put forward as promising targets for new anti-microbial therapeutics [1]. Several different communication systems have been identified in bacteria,both for intraspecies and for interspecies communication.The AI-2 signal is hypothesized to be involved in interspecies bacterial communication, since it is produced by an enzyme, LuxS, which is widely conserved among Gram-negatives and Gram-positives [2]. 【总页数】4页(966-969) 【关键词】

【作者】Inge M Thijs;Sigrid CJ De Keersmaecker;Hui Zhao;Ami De Weerdt;Kristof

Engelen;David

De

Coster;Geert

Schoofs;Michael

McClelland;Jos Vanderleyden;Kathleen Marchal

【作者单位】Centre of Microbial and Plant Genetics, KU Leuven,