针药复合麻醉对术后肠梗阻大鼠肠动力的保护作用和对小
肠局部环氧合酶2和胃动素的调控
汪雯;房军帆;杜俊英;陈宜恬;邵晓梅;方剑乔
【期刊名称】《浙江中医药大学学报》 【年(卷),期】2014(000)003
【摘要】[Objective] To observe the protective effect of combined acupuncture and medicine anesthesia on intestinal motility in postoperative ileus(POI) rats, and discuss the possible mechanism preliminarily. [Methods] 30 male rats were randomly divided into sham operation group(Control group), single general anesthesia group(Model group) and combined acupuncture and medicine group(EA group). Then the POI model was built, during which the two types of anesthesia method were used. 3h after POI molding, the changes of intestinal motility were recorded in each group, while the expression of cy-clooxygenase 2(COX-2) and motilin were detected by enzyme-linked immunosorbent assay(ELISA).[Results] Compared with Control group, the intesti-nal motility of rats in Model and EA groups decreased extremely at 3h after molding( P<0.01), with EA group better than that of Model group( P<0.01). However, at the same time, COX-2 expression in Model and EA groups showed no obvious change compared with that of Control group( P>0.05), the same was with that in motilin expression between Control and EA groups( P>0.05), but the motilin
针药复合麻醉对术后肠梗阻大鼠肠动力的保护作用和对小肠局部环氧
