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基因工程与生物药物
姓名：李华龙
班级：生物制药1301 学号：1302150003
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摘要
自1972 年DNA重组技术诞生以来,生命科学进入了一个崭新的发展时期。以基因工程为核心的现代生物技术已应用到农业、医药、轻工、化工、环境等各个领域。它与微电子技术、新材料和新能源技术一起,并列为影响未来国计民生的四大科学技术支柱, 而利用基因工程技术开发新型生物药物更是当前最活跃和发展迅猛的领域[ 1]。从1982年美国 Lilly 公司首先将重组人胰岛素投放市场,标志着世界第一个基因工程药物的诞生。 基因工程制药作为一个新兴行业得到各国政府的大力支持, 各国都积极研究和开发各种基因工程药物,并取得了丰硕成果。本文通过对基因工程药物的开发、应用和研究方法等研究进展进行综述。
Abstract
Since 1972, DNA recombinant technology was born, life science has entered a new period of development.Gene engineering as the core of modern biotechnology has been applied to agriculture, medicine, light industry, chemical industry, environment and other fields . It and microelectronic technology, new materials and new energy technologies together, tied for the four future beneficial to the people's livelihood the big pillar of science and technology, and using genetic engineering technology to develop new biological drugs is the most active and rapidly developing field. From the United States in 1982 Lilly's first recombinant human insulin on the market, marking the birth of the world's first gene engineering medicine. Genetic engineering pharmaceutical as an emerging industry has received great support from governments the countries are actively research and development of various genetic engineering drugs, and achieved fruitful results. In this paper, through the development of gene engineering medicine, research and Application Research progress is reviewed in this paper.
关键词
基因工程、生物药物、研究进展、应用
Genetic engineering、 biological medicine、 research progress,、application
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目录
一、基因工程 ........................................................................................................................... 4 二、基因工程药物 ................................................................................................................... 4 三、基因工程制药概述 ........................................................................................................... 4 四、基因工程药物的开发 ....................................................................................................... 4
4.1基因工程菌发酵制药 ................................................................................................. 4 4.2基因工程动物细胞培养制药 ..................................................................................... 5 4.3转基因植物生物反应器制药 ..................................................................................... 5 五、基因工程药物的应用 ....................................................................................................... 5
5.1生理活性物质的生产 ................................................................................................. 6 5.2抗体的生产 ................................................................................................................. 6 5.3用于生产疫苗 ............................................................................................................. 6 六、几种基因工程药物研究进展 ........................................................................................... 6
6.1白介素(IL) .................................................................................................................. 6 6.1重组疫苗 ..................................................................................................................... 7 七、前景和展望 ....................................................................................................................... 7 八、参考文献 ........................................................................................................................... 7
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基因工程与生物药物
