硫必利与利培酮治疗老年痴呆精神行为症状的对比研究
袁成勇
【期刊名称】《中国继续医学教育》 【年(卷),期】2015(007)015
【摘要】Objective To study the clinical application of risperidone in the treatment of behavioral and psychological symptoms of dementia and tiapride therapy differences behavioral and psychological symptoms of dementia and related side effects. Methods Experimental group were treated with tiapride (50~400 mg / qd), the control group received risperidone (0.5~4.0 mg) /qd).6 weeks Differences between the two groups and the PANSS scale Results TESS data. Results Efifciency difference was not statistically significant (P>0.05) tiapride treatment group the number of cases of side effects than risperidone group, the Results were statistically significant (P < 0.05). Conclusion Tiapride treat mental and behavioral symptoms of senile dementia exact effect.%目的 分析临床应用利培酮治疗老年痴呆精神行为症状与硫必利治疗老年痴呆精神行为症状的疗效差别及相关副反应.方法 选取伴有精神行为症状的老年痴呆患者150例,并按随机数字表法将患者随机分为两组各75例,实验组患者给予硫必利(50~400 mg/qd),对照组给予利培酮治疗(0.5~4.0 mg/qd).6周后比较两组PANSS量表和TESS量表结果的差异.结果 硫必利治疗组总有效率为94.7%,利培酮治疗组总有效率为92.0%.两组结果对比:有效率差异不具有统计学意义(P>0.05).硫必利治疗组发生副反应的病例数少于利培酮治疗组,结果具有统计学