男性2型糖尿病患者25羟基维生素D的水平变化及与骨
密度的关系
王爱霞;詹志伟;李全民;赵保明
【期刊名称】《中国实用医刊》 【年(卷),期】2013(040)022
【摘要】目的 探讨男性2型糖尿病(type 2 diabetes mellitus,T2DM)患者血清25羟基维生素D[25-(OH)D3]水平的变化,以及25-(OH) D3水平与骨密度(bone mineral density,BMD)的关系.方法 87例男性T2DM患者为病例组,均行腰椎及髋部双能X线骨密度测定,同期男性健康体检者90名为正常对照组.用酶联免疫法检测各组25-(OH) D3水平及相关临床和生化指标.比较两组25-(OH) D3的水平以及25-(OH) D3与男性病例组BMD的相关性.结果 ①病例组25-(OH) D3水平为(10±4)ng/ml,对照组为(12±4)ng/ml,T2DM组25-(OH)D3明显低于对照组(P＜0.05).②病例组骨质疏松症(osteoporosis,OP)患者25-(OH) D3为(10±3)ng/ml,无OP患者为(9±4)ng/ml,两组比较差异无统计学意义(P＞0.05).结论 男性2型糖尿病患者25-(OH) D3水平明显降低,25-(OH) D3与骨密度无明显相关性.%Objective To investigate the serum changes of 25-hydroxyvitamin D level in the male patients with type 2 diabetes,and the relationships between 25-hydroxyvitamin D level and bone mineral density.Methods Eighty-seven male patients with type 2 diabetes mellitus were selected as the case group,and 90 male healthy people were selected as the control group.ELISA were used for the detection of serum 25-hydroxyvitamin D,relevant clinical and
biochemical index were also detected.Then the serum differences of 25-hydroxyvitamin D levels in the two groups were contrasted and the relationship between 25-hydroxyvitamin D and the T2DM male patients was analyzed.Results ①Serum 25-hydroxyvitamin D level of T2DM group was significantly lower than that of the control group(P ＜0.05).②There was no significant difference in serum 25-hydroxyvitamin D level between osteoporosis patients group and no osteoporosis patients group in T2DM group (P ＞ 0.05).Conclusions Serum 25-hydroxyvitamin D level in male patients with type 2 diabetes was significantly lower than that of control group.No correlation was found between serum 25-hydroxyvitamin D level and bone mineral density in male patients with type 2 diabetes. 【总页数】3页(4-6)
【关键词】男性;2型糖尿病;25羟基维生素D;骨密度;骨质疏松症 【作者】王爱霞;詹志伟;李全民;赵保明
【作者单位】455000 河南省安阳市人民医院内分泌二科;北京市第二炮兵总医院内分泌科;北京市第二炮兵总医院内分泌科;455000 河南省安阳市人民医院内分泌二科
【正文语种】中文 【中图分类】 【文献来源】
https://www.zhangqiaokeyan.com/academic-journal-cn_chinese-
journal-practical-medicine_thesis/0201255295379.html 【相关文献】
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男性2型糖尿病患者25羟基维生素D的水平变化及与骨密度的关系
