二甲双胍联合克罗米芬用于多囊卵巢综合征的临床效果观
察
梁莹
【期刊名称】《中国社区医师》 【年(卷),期】2014(000)017
【摘要】目的：探索二甲双胍联合克罗米芬用于治疗多囊卵巢综合征(PCOS)致不孕的临床效果。方法：2012年1月-2013年12月收治PCOS并不孕患者168例，随机分为试验组80例与对照组88例。试验组给予二甲双胍联合克罗米芬治疗，对照组给予克罗米芬治疗。比较两组用药前后雌激素、胰岛素的变化及排卵妊娠情况。结果：试验组与对照组经治疗后，FSH、LH、T、胰岛素较治疗前均有所改善，差异均有统计学意义(P＜0.05)，而且试验组各项指标改善情况均优于对照组(P＜0.05)。试验组98个周期排卵率85.7%，妊娠率31.6%；对照组118个排卵周期排卵率69.5%，妊娠率20.3%。试验组的排卵率与妊娠率均高于对照组，差异具有统计学意义(P＜0.05)。结论：二甲双胍联合克罗米芬治疗多囊卵巢综合征能提高排卵率和妊娠率。%Objective:To investigate the clinical effect of metformin combined with clomiphene in the treatment of polycystic ovary syndrome(PCOS).Methods:168 cases with PCOS and infertility were selected from January 2012 to December 2013.They were randomly divided into the experimental group with 80 cases and the control group with 88 cases.The experimental
group
were
given
metformin
combined
with
clomiphene,while the control group were given clomiphene citrate.We
二甲双胍联合克罗米芬用于多囊卵巢综合征的临床效果观察
