pN2Ⅲ期非小细胞肺癌患者术后生存的影响因素
吴骁伟;陈滔;尹随;邓豫;赵波
【期刊名称】《中华肿瘤杂志》 【年(卷),期】2018(040)010
【摘要】Objective To investigate the effect of mediastinal lymph node resection, metastasis status and treatment on the prognosis of patients with stage Ⅲ-pN2 non-small cell lung cancer (NSCLC). Methods Clinical data of 206 patients who were pathologically diagnosed as stage Ⅲ-pN2 NSCLC in Tongji Hospital from July 2006 to Dec 2009 were retrospectively analyzed and followed up. Log rank test and Cox proportional hazards regression model were used to analyze the prognostic significance of mediastinal lymph node excision, metastasis state and treatment. Results The median overall survival (OS) time of the whole group was 29.6 months, and the median disease-free survival ( DFS) time was 27. 2 months. Univariate analysis showed that the less number of mediastinal lymph node stations with metastasis (single station), the less number of mediastinal lymph nodes involved ( less than 2), and postoperative chemotherapy were associated with longer postoperative OS and DFS time (P<0.05 for all). The patients with skip metastasis, negative metastasis of subcarinal lymph node, the lower mediastinal lymph node metastasis rate (MLNR<33％) and postoperative radiotherapy had longer OS and DFS time than those
pN2Ⅲ期非小细胞肺癌患者术后生存的影响因素
