PKC在青壮年猝死综合征心肌组织中的变化
徐宏泉;竞花兰;张宜骏;闫记全;温涌溪;林泓;姜富学
【期刊名称】《中国法医学杂志》 【年(卷),期】2009(024)006
【摘要】Objective This article aims to explore the relationship between PKC and SMDS(sudden manhood death syndrome,SMDS).Methods By way of immunohistochemical staining of left,right ventricular tousles,sino atrial node and atrioventricular node from 30 cases of SMDS group and 20 cases of control group,we observed and measured the expression and the intensity variance of PKC in myocardial ceHs with graphical analysis software.Results The average gray value and total area of PKC in myocardial cells of cases in the SMS group are obviously higher than that of cases in control group(P<0.05).And in the SMDS group,the average gray value of PKC in sino atrial node is higher than that in atrioventricular node.Conclusion As one way of humoral regulation,PKC is involved in the process of protecting the heart from impairment in SMDS.and it can be considerated as a reference index to identify the SMDS.%目的 探讨蛋白激酶c(PKC)与青壮年猝死综合征之间的关系.方法 取30例青壮年猝死综合征、20例正常对照心脏标本的左右心室肌、窦房结、房室结组织,通过免疫组化学染色,应用图像分析软件对PKC分布及强度变化进行定最检测分析,并进行统计学处理.结果 青壮年猝死者心肌细胞PKC平均灰度值及面积代数和显著高于正常对照组(P<0.05);其中青壮年猝死者安房
PKC在青壮年猝死综合征心肌组织中的变化
