多模态MRI对双重病理所致颞叶癫痫的诊断价值
成丽娜;汪文胜;郭圣文;赖春任;赵地;沈君
【期刊名称】《实用放射学杂志》 【年(卷),期】2018(034)012
【摘要】目的 研究多模态 MRI对双重病理(DP)所致颞叶癫痫(TLE)的诊断价值.方法 采用基于体素形态学分析(VBM)及体素分析(VBA)DP所致TLE 36例(左侧组 20例,右侧组 16例)在 T1WI 灰质体积、指数化表观扩散系数(eADC)、脑血流量(CBF)值与正常对照组(3 6例)的差异,并进行统计学分析.结果 T1WI灰质体积、eADC值、CBF值均出现病侧偏侧性降低,有显著统计学差异(FDR校正,P=0.001),且功能像中发现更广范围异常脑区.上述结果存在共同叠加的异常脑区位于病侧颞极(颞上回)、颞极(颞中回)、颞中回、颞下回、梭状回、海马、海马旁回.结论 多模态 MRI检查通过发现叠加异常脑区有助于提高 DP 所致TLE术前致痫灶定位诊断能力.%Objective To investigate the diagnostic value of multimodal MRI for dual pathology (DP)in temporal lobe epilepsy (TLE).Methods The methods of voxel based morphometry (VBM)and voxel based analysis (VBA)had been employed to study the difference between 36 patients (20 cases left group and 16 cases right group)with TLE caused by DP and 36 healthy subjects on the grey matter
(GM)volume,exponential
apparent
diffusion
coefficient
(eADC)and cerebral blood flow (CBF)value.The corresponding statistical study had also been conducted.Results There were significant statistical differences (FDR correction,P=0.001)between healthy subj ects and
多模态MRI对双重病理所致颞叶癫痫的诊断价值
