C-12多肿瘤标志物蛋白芯片检测系统在肺癌诊断中的价值
王勇;卜智斌;张志培;赵渭东;宋少伟;张永辉;李小飞
【期刊名称】《现代肿瘤医学》 【年(卷),期】2011(019)001
【摘要】Objective :To evaluate the diagnostic value of C - 12 multi - tumor markers protein biochip detection system ( C - 12) in lung cancer.Methods : The serum levels of 12 tumor makers ( CA199 , NSE , CEA ,CA242 , Ferritin ,Beta - HCG,AFP, Free - PSA, PSA, CA125, HGH, CA153) were detected in 67 cases with lung cancer ( cancer group) and 69 cases with pulmonary benign diseases ( benign group) and 70 healthy persons ( control group) by C 12.Results : The positive rates were 79.10％ ,30.43％ and 18.57％ in lung cancer, pulmonary benign diseases and heahhy groups respectively.There was significantly higher positive rate in cancer group than those in the benign group and the control group( P ＜0.01) .The positive rates of CEA , CA125 ,NSE, CA199 and CA242 in cancer group were significantly different compared with those in the benign group and control group( P ＜ 0.05 ).Positive rate of CEA was the highest in lung adenocarcinoma than others, while positive rate of NSE was the highest in small cell lung cancer than others.Conclusion; The early clinic diagnosis rate of lung cancer can be improved by the applicaion of C - 12 in lung cancer, and the combined tests of CEA,CA125 ,NSE,CA199 and CA242 are more economic and
C-12多肿瘤标志物蛋白芯片检测系统在肺癌诊断中的价值
