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DNA定量分析系统在宫颈病变中的应用
作者:梁海红 王文普 沈莹 张爱丽 张凯 张丹 来源:《医学信息》2020年第15期
摘要:目的; 探讨细胞DNA定量分析系统在宫颈癌及癌前病变诊断中的应用价值。方法; 选择2019年7月~2020年4月在天津港口医院门诊就诊并进行检查的1226例患者为研究对象,将其中采用DNA定量分析技术(包括DNA倍体分析和液基细胞学TCT技术)检测的704例设为实验组,行单一液基细胞学检测的522例设为对照组。以宫颈活检病理结果为诊断标准,对两组检出阳性率及实验组组内两种方法的敏感性和特异性进行比较。结果; 实验组共检出阳性患者129例(18.32%),活检阳性患者57例(58.16%);对照组检出阳性患者72例(13.79%),活检阳性患者30例(41.67%),差异有统计学意义(P 关键词:DNA倍体分析;液基细胞学;癌前病变
中图分类号:R737.33; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;文献标识码:A; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ;DOI:10.3969/j.issn.1006-1959.2020.15.052
文章编号:1006-1959(2020)15-0164-03
Abstract:Objective; To explore the application value of cellular DNA quantitative analysis system in the diagnosis of cervical cancer and precancerous lesions.Methods; A total of 1,226 patients who were examined in the outpatient clinic of Tianjin Port Hospital from July 2019 to April 2020 were selected as the research subjects, and DNA quantitative analysis techniques (including DNA ploidy analysis and liquid-based cytology TCT technology) were used for detection. Of 704 cases were set as the experimental group, and 522 cases with single liquid-based cytology were set as the control group. Using the pathological results of cervical biopsy as the diagnostic criteria, the
DNA定量分析系统在宫颈病变中的应用
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